Sabinene: A New Green Solvent Used in the Synthesis of Thiazolo[5,4-b]pyridines by Thermal or Microwave Activation - Université d'Orléans Accéder directement au contenu
Article Dans Une Revue Molecules Année : 2023

Sabinene: A New Green Solvent Used in the Synthesis of Thiazolo[5,4-b]pyridines by Thermal or Microwave Activation

Résumé

Following the work already carried out in our laboratory on eucalyptol, a new green solvent derived from biomass, we are now looking at sabinene as another new green solvent. Sabinene is also derived from biomass, has no known toxicity and can be recycled by distillation. We have shown that it can be used as it is or distilled to synthesize thiazolo[5,4-b]pyridine heterocycles by thermal activation or microwave irradiation. This new solvent was compared with various conventional and green solvents. The conditions were optimised to enable us to carry out the syntheses in satisfactory yields, and we were able to show that sabinene, a natural bicyclic monoterpene, could be used effectively as a solvent.

Domaines

Chimie

Dates et versions

hal-04548242 , version 1 (16-04-2024)

Identifiants

Citer

Gatien Messire, Véronique Ferreira, Emma Caillet, Lyana Bodin, Amélia Auville, et al.. Sabinene: A New Green Solvent Used in the Synthesis of Thiazolo[5,4-b]pyridines by Thermal or Microwave Activation. Molecules, 2023, 28 (19), pp.6924. ⟨10.3390/molecules28196924⟩. ⟨hal-04548242⟩
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